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Alright, which ones have you read?

In Aliens: Rogue, decades of research involving genetic engineering with xenomorphs and their DNA Reflex spawned a massive chimera called the Rogue. Many called it a male queen, but this is actually inaccurate... It was no more than a gigantic freak of utter rage and sadism. Though it didn't care about people who were held still, it would attack virtually anything that moved and actually exchanged dialogue with the queen, threatening her from what I can gather. With his actions afterward, I can only assume her responses were along the lines of "ha! Try me, newbie..." He broke out and mtore through the facility he was born in, ripping apart the gates to the containment chamber and allowing the queen's conveniently placed drones flood out into the colony and overtake it. When he got to her and they fought, he got off one good hit then was swiftly and brutally slaughtored by her. He even started tearing his corpse to shreds after winning.

In Aliens: Music of the Spears, it was revealed the marines had trained a massive drone they called Blue to search for illegally transported hive matereals, things like eggs and royal jelly. He had restraints, but they weren't that effective and it was actually rather obvious he could have easily overtaken the marines had he wanted. But he for some reason never did. When they were using him to track the illegally imprted drone, mozart, he got loose from them apon catching a whif of the drug xeno-zip, made from royal jelly. He found the addict using it in the alleyway, grabbed him, and repeatedly smashed him against a brick wall until he was essentially a bloodied pulp. He never did die, but unfortunately he never got to confront Mozart either.

In Aliens: Labyrinth, one professor who was for the most part now prosthetics was working with studying xenomorph behavior and found that half starved xenomorphs began to wither and even a certain organ in their brain case seemed to shrivel up smaller and smaller under these conditions. With the smaller organ, xenomorphs could not be completely controlled by could be "guided" by strong mental forces. most notably from people who had taken drugs designed to temporarily heighten one's awareness. Unfortunately, this method almost invariably caused death of the drone ultimately through malnutrition. They probably could have put themselves into stasis, but he also kept them awake when he wanted them by electrocution. He had one he named Trixie, and would walk him through the corridors on a very large metal harness that kept Trixie unable to stand upright, use his tail, or bite.

Sounds good so long as they're careful. Most drones are only about as smart as a dog anyway and would react appropriately... But they would still have to be careful since the same tactic wouldn't work if they were to try it on a queen or if she could communicate with her kin. Nor would it work on an alpha or praetorian, though they could be fooled if the people were to look like xenos as well so long as the people didn't do anything not-xenomorphic. But I suppose a sort of screening process could weed out the alphas and, in turn, the future praetorians.