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I can help ya here!
Okay use Momo,Ziggy,Kos-mos PUT THEN IN THAT ORDER IN BATTLE!
At the beginning stock all three,and then attack her at her zones which are B-C-BB(Square,Triangle,circle,circle)If you have a boost and its Ziggy's turn make him do that combo and she might hit a down zone then boost up either Momo or Kos-mos to attack her from the ground using the same combination.If you have another boost(which will help A LOT)You can do it again with who ever.It WILL take a lot of damage if you have your characters leveled up good.When manes awakens,it will tell you,her zone will then be C-B-B(Triangle,square,circleadd more circle if you want to do more damage)Of course Momo wont be able to do those BUT she is good for healing.Have Medica,Medica 2,and try to have Medica All,and also Revert,when I was fighting her my Momo het getting knocked out so ya...repeat all of the above until she is DEAD!Try to have all of them have the same healing spells.If you have trouble doing the stocks cuz your HP is always llow,you would probably want to level up.Keep your HP high cuz she does LOTS of damage!Also there are these spells you can learn to lower physical(sorry bout spelling) attack,use that when she uses her HP to raise her attack,that would make it a little easier.There are some things that will raise other things like boost and quick,watch out for those.She uses poison a lot so have all of them have poison protection.LAST,remember to steal the awakening,do it at the beginning of the battle,if you dont get it,try again BUT NOT WHILE SHE'S IN MANES MODE!
Good Luck!

Heh, I beat her already and I never got to mention it in this thread, sorry, but thanks for the help BTW xd

Now I'm on Old Miltia trying to get through that stupid room.

Beat it ^^

I just beat Margulis, and now I'm in the Kukai Foundation doing GS Quests. I just tried that man's who put a bug in the Encephalon but I can't find the bug. He said somewhere sunny and private.

I think that's in Sakura's summer subconcious domain?

Ok here's what you need to do.

Start this battle with Shion, KOS_MOS, and Jin. Strenthen their attacks by using Thunder Sword on KOS-MOs and Jin. Stock up and launch a series of attacks. Either Jin or KOS-MOS should lead the assault to put Orgulla in the Air. Boost the others behind the leader and unload with everything in their arsenal. Make sure one or two of these fighters have the Medica All Skill. Orgulla's scatter attack can be a major problem without it.

Nearly halfway through the battle, Orgulla's pose changes and so do her attributes. Switch Shion and Jin out of the party in favor of Ziggy and either MOMO or Jr. Orgulla's attack power increases greatly in this new stance, so MOMO's low HP may be a problem if the boss targets her. Infuse KOS-MOS, MOMO/Jr. with the power of fire by using Flame Sword on them. Stock up again and unleash a chain of attacks starting with Ziggy this time. He Downs the enemy instead of making her airborne. KOS-MOS Airs the opponent if she leads, which puts her out of Ziggy's reach. Note that defeating Orgulla in her Manes (blue sword) form awards twice the C. Pts.

Orgulla may return to her original stance if it take sthe party too long to finish her off, If so, change back to the original battle formation to finish her off, etc.

My beat time for this brat was 41:50, and that was about my tenth try at beating her. She changed forms about four times through that battle. It was really a pain in the butt. The encephalon dive challenge was tough, but took less time than it took me to beat Orgulla.
If I hear "Filthy impure flesh" one more time...