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for me it was when Ryan busted the neon light on Drew's desk

Mine was during the gag reel where Drew kept pressing the buzzy button while the director talked and then it cuts to a shot of Colin and Ryan holding their heads or scream in agony.

I liked the whole "THE CAT" Segment....and of course we can never forget Colin's undieing "Joe had a nice bone!"

xDD I was going to say that!!

I also loved Brad ( I believe it was brad's ) when they were doing the movie and he said "I rode your mom all the way in here"

Also, in bartender with Chip and Wayne. "Im the chocolate, and youre the chip!"

I also love when they having running jokes making fun of Colin's shirts or Ryan's shoes.

My friend and I used to watch the show religiously, and we saw the comercial when ryan sang "You and your Constipation". We would watch every episode in hopes of seeing that, but we never did. We did get a great inside joke though...

Me: -sings- You...and your constipation!
Her: You werent supposed to tell anyone! gonk


Edit: Sorry, one last one! xD I loved when Colin was in front of the green screen where the cop was stripping.

Yeah, I have a few more. lol.

Amen to the Richard Simmons episode.

"But...but whos going to move Wayne??"

Also, one of the Show Stopping number ones, with the swiss cheese factory.

"Without a hole, where would you be?"

The pantsa song
Tapioca
Wayne wearing a GString
Greg's cricket hoedown
Brad's Neroshi Song
Nina and Vina duet

two words : Nice Pants